The world's most wanted master thief, Lupin the Third is dead! Despite a coroner's report, Interpol Inspector Zenigata is skeptical and discovers that Lupin is actually alive and well and stealing! But who had set up Lupin's death and why?
For now, questions are set aside, as Lupin, Jigen and Goemon immediately embark to Egypt to pilfer a stone artifact from a pyramid, with Zenigata in hot pursuit. Fujiko, lured by the promise of eternal youth and beauty by the sinister and enigmatic scientist known as Mamo, doublecrosses Lupin and steals the stone. Her betrayal causes a rift between Lupin and his cohorts, causing the trio to split up, but eventually leads Lupin to Mamo's hideaway, where he discovers the madman's dark secret and a fiendish scheme that threatens the entire planet!
Now, it's up to Lupin to stop the insane Mamo-before he can complete his 10,000 year-old plans of world domination.